ICOS Corporation

Research Associate, Target Validation

ICOS Corporation, based in the Seattle, Washington area, is committed to advancing science in the areas of protein based and small molecule therapeutics with a world-class research and development organization. Our lead product Cialis® (tadalifil) for the treatment of erectile dysfunction (ED) has received US FDA approval and is currently sold in over 50 countries.

If you are a Research Associate interested in working with a fast growing company that is building a strong pipeline of pharmaceutical products in multiple stages of development, then consider this opportunity with ICOS Corporation

Responsibilities:

• Performing biochemical and cell-based assay development, validation and implementation.
• Testing of proteins and small molecules in cell-based and biochemical assays.
• Cloning and protein expression in mammalian systems.
• Establishment and characterization of mammalian stably transfected cell lines.
• Mammalian cell line culture.
• Flow cytometry analysis.
• Protein characterization (SDS PAGE, western, ELISA, etc.).
• Data analysis and interpretation.
• Collaborating with and communicating data to several groups.

Requirements

• BS or MS (preferred) plus a minimum of 2 years relevant experience.
• Competency in development and validation of cell-based assays.
• Experience with DNA and RNA molecular biology techniques (PCR, restriction digests, cloning, rt-PCR, etc.).
• Excellent sterile technique.
• Working knowledge of Immunology a plus.
• Previous experience in flow cytometry analysis.
• Strong collaborative skills.
• Detail oriented and organized.
• Excellent written and oral communication skills.
• High degree of creativity and problem solving capability.

ICOS offers a highly competitive compensation package and a friendly, collaborative culture that values personal initiative and professional achievement.

For immediate consideration visit www.icos.com and apply directly for this position or email your resume directly to kfenstermacher@icos.com highlighting this position.

Learn more about ICOS' philosophies, attributes, financial information, and more by visiting our web site at: www.ICOS.com.

ICOS Corporation
Reference Job Code: 1687LG0704
Karen Fenstermacher

Email: kfenstermacher@icos.com

ICOS Corporation is an Equal Opportunity Employer

Submitted: 07/21/2004