Ikaria, Inc.

Scientist/Senior Scientist, ADME/Toxicology

Ikaria is an exciting new company located in Seattle dedicated to the development and commercialization of new products based on reversible metabolic control for its use as a treatment for acute trauma, during surgery and extending the length of time that organs and tissues are viable for transplantation.

Description:

We are seeking a Scientist/Senior Scientist to join our Preclinical Pharmacology Group. The successful candidate will be a skilled and enthusiastic ADME/Toxicologist to support our lead projects.

Responsibilities:

1. Develop and implement protocols for the pharmacokinetic and toxicologic characterization of Ikaria’s metabolic regulators and their metabolites.
2. Conduct preliminary ADMET studies in-house.
3. Collaborate with bioanalytical scientists to develop and implement assays for biomarkers.
4. Manage pharmacokinetic and toxicologic studies at CRO’s.
5. Participate in efficacy pharmacology studies, as needed.
6. Contribute study reports for inclusion in regulatory filings.
7. Train and supervise research associate(s).
8. Communicate important findings and results to management. Make presentations within Ikaria as well as at external scientific meetings.

Requirements:

1. PhD or DVM with pharmacology or toxicology expertise plus a minimum of three (3) years (Scientist) or five (5) years (Senior Scientist) experience in pharma and/or biotechnology.
2. Proven experience with pre-clinical development of small molecule therapeutics.
3. Prior experience developing parenteral products desirable.
4. Documented track-record in contributing ADME/Tox data to IND applications.
5. Experience in outsourcing and monitoring GLP studies to support regulatory filings.
6. Excellent verbal and written communication skills.
7. Previous supervisory experience desirable.
8. Ability to work both independently and as part of a team.
9. Proficiency with relevant software packages.

Visit us at www.ikaria.com.

Ikaria is an Equal Opportunity Employer, committed to hiring the best qualified individuals and giving them the opportunity to stretch their abilities.

Please reference Job Code: 06-03WABIO when applying and submit your CV and cover letter by Mail or Email:

Ikaria, Inc.
Reference Job Code: 06-03WABIO
Attn: Human Resources – Job code: 06-03WABIO
1616 Eastlake Ave. East, Suite 207
Seattle, WA 98102
Email: hr@ikaria.com

Ikaria, Inc. is an Equal Opportunity Employer

Submitted: 02/06/2006